| Rank | Player | Yards | Games Played | Years Played | Teams Played For |
|---|---|---|---|---|---|
| 1 | *Jim Brown | 8514 | 82 | 1960-1965 | Browns |
| 2 | *Jim Taylor | 7898 | 109 | 1960-1967 | Packers, Saints |
| 3 | Don Perkins | 5402 | 93 | 1962-1968 | Cowboys |
| 4 | Dick Bass | 5264 | 100 | 1961-1969 | Rams |
| 5 | Bill Brown | 4868 | 124 | 1961-1969 | Bears, Vikings |
| 6 | *Gale Sayers | 4866 | 64 | 1965-1969 | Bears |
| 7 | *Leroy Kelly | 4553 | 82 | 1964-1969 | Browns |
| 8 | *John Henry Johnson | 4381 | 67 | 1960-1965 | Steelers |
| 9 | Tom Matte | 3859 | 120 | 1961-1969 | Colts |
| 10 | Dick Hoak | 3850 | 123 | 1961-1969 | Steelers |
| 11 | Tommy Mason | 3769 | 95 | 1962-1969 | Vikings, Rams |
| 12 | Nick Pietrosante | 3579 | 105 | 1960-1967 | Browns, Lions |
| 13 | Ken Willard | 3575 | 69 | 1965-1969 | 49ers |
| 14 | Timmy Brown | 3524 | 94 | 1960-1968 | Colts, Eagles |
| 15 | J.D. Smith | 3427 | 84 | 1960-1966 | Cowboys, 49ers |
| 16 | Amos Marsh | 3222 | 95 | 1961-1967 | Cowboys, Lions |
| 17 | Ernie Green | 3204 | 89 | 1962-1968 | Browns |
| 18 | Earl Gros | 3155 | 107 | 1962-1969 | Packers, Eagles, Steelers |
| 19 | Tom Woodeshick | 3121 | 94 | 1963-1969 | Eagles |
| 20 | John David Crow | 2813 | 86 | 1962-1968 | 49ers, Cardinals |
| 21 | *Fran Tarkenton | 2672 | 126 | 1961-1969 | Vikings, Giants |
| 22 | Ronnie Bull | 2657 | 98 | 1962-1969 | Bears |
| 23 | Jerry Hill | 2553 | 90 | 1961-1969 | Colts |
| 24 | Johnny Roland | 2524 | 55 | 1966-1969 | Cardinals |
| 25 | Tom Moore | 2445 | 102 | 1960-1967 | Falcons, Packers, Rams |
| 26 | Dan Lewis | 2437 | 76 | 1961-1966 | Lions, Giants, Redskins |
| 27 | *Paul Hornung | 2401 | 68 | 1960-966 | Packers |
| 28 | Clarence Peaks | 2328 | 70 | 1960-1965 | Eagles, Steelers |
| 29 | Willis Crenshaw | 2228 | 84 | 1964-1969 | Cardinals |
| 30 | Bill Triplett | 2226 | 72 | 1963-1969 | Lions, Giants, Cardinals |
| 31 | Dave Osborn | 2205 | 60 | 1965-1969 | Vikings |
| 32 | Alex Webster | 2184 | 55 | 1960-1964 | Giants |
| 33 | Tony Lorick | 2124 | 83 | 1964-1969 | Colts ,Saints |
| 34 | Les Josephson | 2034 | 69 | 1964-1969 | Rams |
| 35 | *Lenny Moore | 1995 | 70 | 1962-1967 | Colts |
| 36 | Junior Coffey | 1967 | 53 | 1965-1969 | Falcons, Packers, Giants |
| 37 | Prentice Gautt | 1943 | 74 | 1960-1967 | Browns, Cardinals |
| 38 | Rick Casares | 1814 | 64 | 1960-1965 | Bears, Redskins |
| 39 | Dan Reeves | 1813 | 58 | 1965-1969 | Cowboys |
| 40 | Tom Watkins | 1791 | 75 | 1961-1968 | Browns, Lions, Steelers |
- * – Member of the NFL Hall of Fame
- Player – Gallery Available
